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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
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N3-Cho bromide (Azido-choline bromide) is an azide-functionalized choline analogue used as a click chemistry reagent to install or label choline head-groups in membrane lipids and related biomolecules. It is provided as a colorless to off-white solid-liquid mixture with high purity and good solubility in common solvents, intended for synthetic and labeling applications.
Azide-functionalized choline analogue for click chemistry labeling.
High purity suitable for synthetic and analytical use.
Soluble in water (125 mg/mL) and DMSO (100 mg/mL); ultrasonic recommended.
Storage recommendations for stability: solid at -20°C sealed; in solvent -80°C up to 6 months.
Available in small research pack sizes for laboratory experiments.
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1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, particularly against indolent lymphoid malignancies. Their anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
Broad antitumor activity
Targets indolent lymphoid malignancies
Inhibits DNA synthesis
Induces apoptosis
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Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
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